This recipe for Mississippi pot roast (often called MS pot roast) delivers tender beef slow-cooked with a blend of robust seasonings, pepperoncini, and a touch of butter to form a luscious sauce that elevates every bite; whether you’re using a crock pot, an Instant Pot, or any slow cooking method, the end result is a show-stopping main dish.
In closing, each element from the beef’s seasoning to the unique addition of pepperoncini ensures that this pot roast Mississippi style is both easy to prepare and impressively flavorful, making it the perfect candidate for stress-free weeknight dinners or festive family feasts.

For me, Mississippi pot roast isn’t just a meal it’s a celebration of comfort and simplicity that brings together tender beef, bold flavors, and a hearty sauce that exemplifies the very best of Southern cuisine, transforming even the busiest week into a comforting, satisfying experience.
Ultimately, as you prepare this Mississippi roast recipe, embrace the ease and rich flavors that have made this dish a beloved tradition across kitchens, knowing that every bite offers the perfect balance of tangy and savory notes reminiscent of genuine Southern hospitality.
Equipments for
Having the right equipment is key to achieving a perfectly tender and flavorful Mississippi pot roast, whether you’re utilizing an Instant Pot for speed or a crock pot for that slow-cooked, melt-in-your-mouth texture.
- Slow Cooker/Crock Pot: Ideal for low and slow cooking that yields fall-apart beef.
- Instant Pot or Electric Pressure Cooker: For a faster, still-tender version of Mississippi roast.
- Large Pot or Dutch Oven (optional): For pre-searing the beef or for stovetop finishing if desired.
- Cutting Board and Sharp Knife: For trimming and preparing the beef and vegetables.
- Measuring Cups and Spoons: To accurately measure seasonings, liquids, and condiments.
- Tongs: For safely handling the beef while searing and transferring it.
- Mixing Bowls: For blending spices and marinating the meat.
By assembling these tools, you create the optimal setup for a seamless cooking process, ensuring your Mississippi pot roast comes out perfectly tender and bursting with flavor every time.
Ingredients for
The ingredients for this Mississippi pot roast have been carefully selected to combine hearty, Southern flavors with an easy, no-fuss approach, resulting in a dish that boasts succulent beef, tangy pepperoncini, and a rich, savory sauce that truly exemplifies comfort food.
For the Beef:
3–4 lbs beef chuck roast – cut into large chunks if desired
Salt and freshly ground black pepper – to season the beef liberally
2 tsp garlic powder
2 tsp onion powder

For the Cooking Base and Sauce:
1 packet (1 oz) ranch dressing mix
1 packet (1 oz) au jus gravy mix
1/2 cup unsalted butter (1 stick) – cut into cubes
1/2 cup pepperoncini juice – from a jar of pepperoncini peppers
1 jar (16 oz) pepperoncini peppers – drained (reserve some extra juice for added flavor, if desired)
For Optional Vegetables:
1 large onion, sliced (optional, adds extra depth of flavor)
2-3 garlic cloves, minced (optional, to boost aroma and taste)
For Adjusting Consistency (Optional):
2 cups beef broth – if a thinner sauce is desired; adjust liquid to preferred consistency
By gathering these carefully balanced ingredients, you create the ideal flavor profile for your Mississippi pot roast a dish where savory, tangy, and buttery notes all come together to deliver a truly irresistible meal.
Instructions to
Follow these detailed, step-by-step instructions to create your Mississippi pot roast, adapting the process whether you’re using a crock pot for slow, hearty cooking or an Instant Pot for a quicker, equally succulent result.
Season and Prep the Beef:
– Generously season your beef chuck roast on all sides with salt, pepper, garlic powder, and onion powder.
– (Optional) If desired, sear the beef in a large pot or skillet with a bit of oil over high heat until all sides are browned. This step adds extra flavor but can be skipped for a simpler method.
Set Up the Slow Cooker/Instant Pot:
– Slow Cooker: Place the beef in the slow cooker.
– Instant Pot: Transfer the beef to the Instant Pot insert and choose the “Sauté” function if you seared the meat, then cancel before adding liquids.

Add the Flavor Packets and Butter:
– Sprinkle the ranch dressing mix and au jus gravy mix evenly over the beef.
– Place the cubes of butter evenly on top of the beef.
Incorporate the Pepperoncini:
– Pour 1/2 cup of the pepperoncini juice over the beef.
– Add the entire jar of pepperoncini peppers to the pot.
– (Optional) Add sliced onion and minced garlic to enhance the aromatic base.

Add Liquid (if using Extra Broth):
For a thinner sauce, pour in 2 cups of beef broth, adjusting the total liquid depending on how saucy you’d like your roast.
Cooking Methods:
Slow Cooker/Crock Pot:
– Cover and cook on low for 8 hours, or on high for 4–5 hours, until the beef is fork-tender and shreds easily.
Instant Pot/Pressure Cooker:
– Secure the lid, set the valve to “Sealing,” and choose “Manual” or “Pressure Cook” on high pressure for 60 minutes.
– Once the cooking cycle is complete, allow the pot to naturally release pressure for 10–15 minutes, then carefully release any remaining pressure manually.
Finishing the Roast:
– Once the beef is tender, remove it from the pot and shred it using two forks.
– Stir the shredded beef back into the sauce, ensuring it is evenly coated with the tangy, buttery, and savory juices.
– Taste and adjust seasoning with additional salt and pepper if needed.

Serve:
– Serve the Mississippi pot roast hot, spooning generous amounts of the shredded beef and its flavorful sauce over mashed potatoes, rice, or alongside crusty bread.
– Garnish with a few extra pepperoncini peppers on top if desired.
By following these precise steps, you will create a Mississippi pot roast that is tender, bursting with flavor, and versatile enough to suit your preferred cooking method whether it’s a slow-cooked classic or a speedy Instant Pot version.
Allergen Information for
Review the following allergen details to ensure your Mississippi pot roast meets the dietary needs of your guests.
- Dairy: Contains butter; use a dairy-free alternative (such as dairy-free margarine) if necessary.
- Gluten: The recipe is gluten-free if flavor packets and broth are gluten-free; always check labels.
- Salt: Contains high-sodium ingredients; adjust salt if on a restricted diet.
By considering these allergen details, you can confidently serve your Mississippi pot roast, adjusting substitutions to accommodate dietary restrictions without compromising flavor.
Substitutions for
This Mississippi pot roast recipe is highly adaptable, allowing you to make substitutions to match your dietary preferences or available ingredients.
- Protein Alternatives: Substitute beef chuck roast with pork shoulder or a well-marbled brisket for a different flavor profile.
- Liquid: Use a mix of water and low-sodium broth if you prefer a lighter sauce.
- Butter: Replace with dairy-free butter or olive oil for a dairy-free version.
- Flavor Variations: Add additional spices such as smoked paprika or a dash of hot sauce for extra depth or heat.
By embracing these substitutions, you can customize your Mississippi pot roast to create a personalized, delicious dish that suits your unique taste and dietary needs.
Variations of
Feel free to experiment with variations of this recipe to create your ideal Mississippi pot roast experience—each method delivers a slightly different texture and depth of flavor.
- Instant Pot Mississippi Roast: Use an Instant Pot for a quick, pressure-cooked version that still yields tender, flavorful beef.
- Crock Pot Mississippi Roast: Stick with a traditional slow cooker for a hands-off, melt-in-your-mouth result.
- Spicy Variation: Incorporate extra red pepper flakes or a few dashes of hot sauce to add a kick of spice.
- Herbed Variation: Add fresh herbs such as rosemary or thyme during the cooking process for an aromatic twist.
- Vegetable Addition: Add carrots, potatoes, or celery to create a heartier, one-pot meal.
- Sauce Adjustment: For a thicker gravy, mix a slurry of cornstarch and water during the last 15 minutes of cooking.
With these variations, you have the creative freedom to reinvent your Mississippi pot roast each time you cook, ensuring that your dish remains exciting, adaptable, and consistently delicious.
Notes on
These practical notes offer additional insights to ensure your Mississippi pot roast turns out perfectly every time, highlighting key techniques for maximum flavor and tenderness.
- For best results, allow the beef to marinate with the seasoning packs for at least 15–30 minutes before cooking.
- Searing the beef is optional but highly recommended to lock in juices and enhance flavor.
- Monitor the liquid during slow cooking; you may need to stir occasionally to prevent sticking.
- The flavor intensifies over time—this dish often tastes even better the next day after the flavors meld.
- If using the Instant Pot, natural pressure release helps maintain tender meat and preserves the sauce consistency.
By keeping these notes in mind, you’ll elevate your Mississippi pot roast to a new level of deliciousness and ensure a consistently flavorful, tender, and richly sauced dish every time you serve it.

Health Benefits of
Mississippi pot roast is not only a comforting meal but also delivers several nutritional benefits when enjoyed as part of a balanced diet.
- Beef: Provides high-quality protein and essential nutrients like iron and vitamin B12.
- Pepperoncini: Adds a tangy, low-calorie boost to flavor without extra fat.
- Broth: Offers hydration and, if made with low-sodium ingredients, a flavorful base without excess calories.
- Herbs and Spices: Contribute antioxidants and anti-inflammatory properties while enhancing flavor naturally.
When enjoyed in moderation as part of a varied diet, Mississippi pot roast offers a delicious way to incorporate lean protein, bold flavors, and comforting warmth, making it a satisfying meal for any occasion.
Nutrition Information
A detailed nutritional breakdown ensures that you can enjoy your Mississippi pot roast while keeping track of its contribution to a balanced diet.
- Calories: 450–500 kcal
- Protein: 35–40 g
- Carbohydrates: 10–15 g
- Fats: 25–30 g
- Vitamins & Minerals: Rich in iron, vitamin B12, and essential minerals from the broth and beef
With this nutritional overview, you can relish each serving of Mississippi pot roast knowing that it provides a hearty, satisfying meal rich in protein and essential nutrients.
Nutritional values can vary based on specific ingredient brands and measurements used. For more precise information, refer to the labels of your chosen ingredients.
Cooking Tips for
These cooking tips will help you perfect your Mississippi pot roast, ensuring that every step from searing the beef to slow-cooking or pressure-cooking is optimized for maximum flavor and tenderness.
- Pat the beef dry thoroughly to ensure a good sear and better flavor absorption.
- Brown the meat in batches to avoid overcrowding and achieve a deep, caramelized crust.
- Use a meat thermometer to check for doneness—tender beef should reach an internal temperature of 190°F–205°F in slow cooker recipes.
- Stir the sauce occasionally during slow cooking to prevent the beef from sticking to the bottom.
- Allow for natural pressure release in the Instant Pot to keep the meat tender.
- Taste the sauce periodically and adjust seasonings before the final cooking stage.
By following these cooking tips, you’ll achieve a Mississippi pot roast that is consistently tender, richly flavored, and perfectly sauced truly a dish worthy of Southern comfort.
Storage Advice for
Proper storage is crucial to preserving the flavor and texture of your Mississippi pot roast for future enjoyment.
- Refrigeration: Store leftovers in an airtight container in the refrigerator for up to 3 days.
- Freezing: Freeze portions in freezer-safe containers for up to 2 months; thaw overnight in the refrigerator.
- Reheating: Gently reheat on the stovetop over low heat, stirring occasionally to retain the sauce’s consistency.
- Labeling: Clearly mark containers with the date of preparation to monitor freshness.
By following these storage practices, you can extend the pleasure of your Mississippi pot roast, ensuring that every bite remains as flavorful and tender as when it was first made.

Serving Suggestions for
Enhance your dining experience with thoughtful serving suggestions that complement the rich flavors of your Mississippi pot roast and create a complete, satisfying meal.
- Mashed Potatoes: Serve the shredded beef over creamy mashed potatoes to soak up the savory sauce.
- Rice or Pasta: Pair with rice or egg noodles for a hearty, comforting plate.
- Crusty Bread: Enjoy with a side of crusty bread to mop up the flavorful juices.
- Steamed Vegetables: Complement the dish with a side of steamed green beans or broccoli.
- Side Salad: A fresh salad dressed in a light vinaigrette provides a refreshing contrast to the rich flavors.
- Pickles: A few extra pepperoncini or pickles on the side offer a tangy, crunchy counterpoint.
With these serving suggestions, your Mississippi pot roast transforms into a complete meal that not only satisfies your hunger but also delights your taste buds with every delicious bite.
Troubleshooting
Should you encounter any challenges while preparing your Mississippi pot roast, these troubleshooting tips offer practical solutions to ensure your final dish is always perfect.
- Issue: Beef is not tender enough.
Solution: Increase the cooking time in your slow cooker or use a natural pressure release in the Instant Pot to allow the beef to become tender. - Issue: Sauce is too thin.
Solution: Remove the lid for the last 15–20 minutes of slow cooking to evaporate extra liquid; for Instant Pot use, select “Sauté” to reduce the sauce. - Issue: Seasoning is too mild.
Solution: Taste the sauce during the last half hour of cooking and adjust with extra salt, pepper, or additional spices like garlic powder. - Issue: The beef is dry.
Solution: Ensure that you do not overcook the beef; if using a pressure cooker, allow for a natural release to maintain moisture. - Issue: Inconsistent flavor.
Solution: Stir occasionally to blend the seasonings evenly; allow the roast to rest after cooking to let flavors meld.
By addressing these common issues with practical solutions, you can confidently overcome any challenges and ensure that your Mississippi pot roast always turns out tender, flavorful, and perfectly sauced.
FAQ About
Beef chuck roast is ideal for its rich flavor and tenderness when slow-cooked.
Yes, the recipe works well in an Instant Pot, reducing cooking time significantly while still producing tender beef.
Allow sufficient cooking time and consider using a natural pressure release (for the Instant Pot) or slow-cooking on low.
It has a tangy, savory flavor profile from the pepperoncini juice and peppers; adjust salt and spices to taste.
Absolutely; adding carrots, potatoes, or celery can turn it into a complete one-pot meal.
Searing is recommended to enhance flavor but can be skipped for a simpler method.
It pairs beautifully with mashed potatoes, rice, pasta, or crusty bread.
Refrigerate in an airtight container for up to 3 days or freeze for up to 2 months.
Yes, add more broth if too thick or simmer uncovered to reduce if too thin.
Absolutely; it scales well and can be made in large batches to feed a crowd.
By addressing these frequently asked questions, you can confidently prepare your Mississippi pot roast, ensuring it meets all your expectations for flavor, tenderness, and hearty satisfaction.
Footnotes for
In conclusion, this Mississippi pot roast recipe is a true celebration of Southern comfort food, combining tender, slow-cooked beef with tangy pepperoncini and savory seasonings to deliver a dish that is as flavorful as it is comforting.
Whether you choose the classic slow cooker method, the speed of an Instant Pot, or the hands-off approach of a crockpot, each version of this recipe offers its own unique twist while remaining true to the rich, robust character of a traditional Mississippi roast.
Embrace the simplicity and bold taste of this dish, experiment with substitutions and variations, and share it with family and friends as a perfect expression of Southern culinary heritage.
For more inventive recipes and culinary inspiration, Navigate to our Main Dishes section, or visit Trustedrecipe, www.spendwithpennies.com or explore additional ideas on Food Network. Thank you for choosing this recipe may every spoonful bring comfort, joy, and a taste of home to your table!